Dissolution Testing

Welcome to the Dissolution Testing section of our web site. Please select one of the categories below for further information:

IntroductiontoDissolutionTesting

One of the main problems facing the pharmaceutical industry is to optimise the amount of drug available to the body i.e. its “bioavailability”. Inadequacies in bioavailability can mean at best that the treatment is ineffective and at worst potentially dangerous (toxic overdose).

Drug release in the human body can be measured in vivo by measuring the plasma or urine concentrations in the subject concerned. However, there are certain obvious impracticalities involved in employing such techniques on a routine basis.

These difficulties have led to the introduction of officialin vitro tests which are now rigorously defined in the respective Pharmacopoeias. Whether or not its numbers have been correlated in vivo, the standard dissolution test is a simple and inexpensive indicator of a products physical consistency.

Subcategories

Welcome to the Dissolution Testers section of our web site.

Welcome to the Dissolution Testing section of our web site. Please select one of the categories below for further information: