Friability Testing

Welcome to the Friability Testing section of our web site. Please select one of the categories below for further information:

Friability Testers Friabimat SA-400 (Granules and Spheroids)

In many cases, such as with hard coated and uncoated tablets, granules and spheroids, it is impossible to determine the friability of the dosage form using a conventional tablet friability tester even if the test time is extended simply because the resistance is such that no measurable attrition is obtained – the energy imparted by the friability tester is just not sufficient to generate quantifiable changes in surface mass.

The Friabimat SA-400 is a new instrument specifically designed to address this particular problem by offering an alternative method of friability measurement.

Friability Testers Model FR 1000/2000 (Uncoated Tablets)

The basic Friability Tester Model FR 1000/2000 comprises of a single or dual drums rotated at a fixed speed of 25 rpm. The standard friability drum has an inside diameter of 287 mm and a depth of 38 mm and is fitted with a curved baffle which subjects the tablets to be tested to a drop of 156 mm. The Friability Tester Model FRV 1000/2000 also features either one or two drums, but allows variable speed between 20 and 60 rpm to be programmed. Number of turns or test duration can also be programmed into the tester.

Introduction to Friability Testing

Friability is the tendency for a tablet to chip, crumble or break following compression. This tendency is normally confined to uncoated tablets and surfaces during handling or subsequent storage.

It can be caused by a number of factors including poor tablet design (too sharp edges), low moisture content, insufficient binder, etc.

For obvious reasons, tablets need to be hard enough such that they do not break up in the bottle but friable enough that they disintegrate in the gastrointestinal tract.